New Delhi: A Delhi court has put on trial BJP MLA Manjinder Singh Sirsa and others in a criminal defamation case filed by Delhi minister Satyendar Jain. Additional Chief Metropolitan Magistrate Samar Vishal framed the notice under Section 251 of the CrPC (dealing with issuance of summons in such complaints) against Sirsa and others and fixed the matter for recording of evidence of Jain and his witnesses on July 17. “The accusation under section 251 CrPC has been explained to counsel for accused Manjinder Singh Sirsa as well as to accused Vishnu Prakash Tripathi and Neetendra Srivastava to which they pleaded not guilty and claimed trial. Put up for post notice complainant’s evidence on July 17,” the judge said. Also Read – Bangla Sahib Gurudwara bans use of all types of plastic items Sirsa has alleged that he was indulging in circulating huge amounts of illegitimate money within the party, Jain claimed. He has also accused a media house for publishing the alleged “libellous and slanderous statements” made by Sirsa. His counsel had said that these allegations were made in front of the national media but only one newspaper published it which shows they were hand in glove with each other. Jain had filed two criminal defamation complaints against rebel AAP MLA Kapil Mishra and BJP leader Sirsa for allegedly defaming him by levelling graft charges against him. If convicted, the offence of defamation entails a maximum punishment of two years. Regarding Sirsa, Jain said that, the MLA made libellous statements by levelling corruption allegation against him. He said that making a statement on the basis of “hearsay” without any proof or evidence supporting it, is not only unbecoming of an MLA, but also a crime of defaming a person.
Ecommerce cos focus on small towns to fuel job opportunitiesEcommerce cos focus on small towns to fuel job opportunities
New Delhi: E-commerce companies are betting big on small towns to explore the opportunities offered by a large customer base and are expanding their talent pool in these cities to fuel growth, experts say. They expect recruitment to go up by 15 per cent in this space. Small towns are becoming the driving force behind e-commerce growth in the country as online retailers are targeting last mile connectivity and are increasingly focusing on getting the small-town Indian customer to shop online. Also Read – Thermal coal import may surpass 200 MT this fiscalExperts said in order to deal with the rising demands of consumers, e-commerce companies have been setting up warehouses in small towns and have also been expanding their talent base in these towns. The sectors that are expected to grow include logistics, e-wallets, FMCG, and retail as these industries have been focusing on tier II and tier III cities growth and have seen customer base grow faster in comparison to metro cities. “Last year Diwali festive sales showed 40 per cent contribution from tier II and III cities. This is a remarkable change and an indication of the reach of e-commerce. Companies are focusing on warehouse, logistics and last mile connectivity. The job market is growing in these cities and will see a growth of 15 per cent in these cities,” Teamlease Services Head of Digital & IT Mayur Saraswat said. Also Read – Food grain output seen at 140.57 mt in current fiscal on monsoon boostWith competition in metro cities reaching saturation, companies have to look for new markets and hence chasing organic growth in these small towns is a natural option, Saraswat noted. Indeed India Managing Director Sashi Kumar said that as per Indeed data, some of the country’s leading unicorns are seeking talent in tier II and tier III locations. “Haryana sees over 18 per cent of job postings from these companies, as does Uttar Pradesh with 8 per cent of all such job postings. Gujarat (2 per cent) and Rajasthan (2 per cent) also see job postings from these companies,” he said. Some of the job roles that are being posted by these companies include ‘delivery person’, ‘guest service agent’, ‘sales manager’, and ‘field executive’, among others. Kunal Sen, India Managing Director, Korn Ferry RPO and Professional Search noted that “it (hiring in small towns) would be around 30 per cent of the overall hiring share but growing faster than the larger towns”. Experts believe that small cities are future centres of retail growth in the country as there is availability of land at cheaper rates, lower rentals and customers are ready to experiment with new format stores.
Quebec man 54 dies on hunting trip in northwestern part of theQuebec man 54 dies on hunting trip in northwestern part of the
VILLE-MARIE, Qc – Police say a companion of a 54-year-old man who died while on a hunting trip in northwestern Quebec could be facing charges in the death.Provincial police say the suspect could be charged as of Monday with charges of criminal negligence causing death, careless use of a firearm and discharging a firearm.Police do not have many details about what happened but say they received a call at 1:30 Saturday morning.They met with one of the deceased’s hunting companions and determined that person to be a suspect.Spokeswoman Helene Nepton did not know how many people were on the trip.The death occurred in Bearn, about 650 kilometres northwest of Montreal.
Japan sees results from Abenomics growth strategy as GDP jumps 35 pctJapan sees results from Abenomics growth strategy as GDP jumps 35 pct
AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email TOKYO – Japan’s economy grew by a stronger-than-expected 3.5 per cent in annual terms last quarter, giving Prime Minister Shinzo Abe a boost as his government tackles reforms needed to ensure a sustained recovery from two decades of malaise.Stronger consumer spending and public works investment coupled with aggressive monetary easing lent oomph to the recovery that began in the last quarter of 2012, when annual growth was 0.3 per cent.The preliminary data for January to March showed the world’s third-largest economy grew 0.9 per cent on a quarterly basis, the fastest pace in a year, according to figures reported by the Cabinet Office on Thursday.Abe took office in late December after voters fed up with years of economic misery returned his Liberal Democratic Party to power. His policies have helped push share prices to their highest levels in over five years, fueled by strong liquidity and expectations of improved profitability for listed companies.But the real test will be whether the gains can be sustained in the longer run, said Masamichi Adachi, an economist with JP Morgan in Tokyo.“It’s not what we can see from just one quarter’s growth,” he said.Demand has been “front-loaded” by a sharp increase in public works contracts and by household purchases being made now to beat sales tax increases in 2014 and 2015. Keeping growth at the 3 per cent or 4 per cent pace needed to counter deflation and tax hikes expected next year is a “mission impossible,” Adachi said. “The sustainability beyond next year, we just don’t know.”The benchmark Nikkei 225 stock index slipped 0.4 per cent Thursday to close at 15,037.24, falling back on profit taking. But it has gained nearly 75 per cent since November in a rally linked to high hopes for Abe’s policies.“Japan’s healthy-looking GDP data are the first substantial piece of good economic news under the Abe government,” said Julian Jessop, an economist with Capital Economics in London.He said it was unclear how much of the rebound could be attributed to Abe’s policy blend, dubbed “Abenomics,” but that “the government can at least claim some credit for boosting confidence in the economy.”The improvement makes it more likely the government will be able push ahead with its pledges to raise sales taxes over the next two years to help improve Japan’s deteriorating fiscal health, said economy minister Akira Amari.Japan’s public debt is more than twice the size of the economy and still growing as the government struggles to revamp aging infrastructure, rebuild from the March 2011 tsunami and meet the social welfare needs of its increasingly elderly and shrinking population.However, top government spokesman, Yoshihide Suga, said the decision on raising taxes would hinge on how the economy performs over the coming months.“Consumer sentiment seems to have recovered,” Suga told reporters. “But at this point we should not be overly optimistic.”“The Abe administration’s policies are starting to see some results, but we need to achieve economic growth with employment and we will work to achieve this.”Apart from soaring share prices, Japan’s manufacturing and employment showed slight improvements in March, buttressing hopes that the economy may be headed for a moderate recovery. The government on Thursday raised its estimate for industrial production in March, saying it rose 0.9 per cent rather than the earlier-reported 0.2 per cent.A sharp decline in the value of the Japanese yen, brought on by monetary easing and by expectations of further easing, has helped some exporters and provided a windfall in yen terms for companies repatriating overseas earnings. But it is also raising costs for many companies that depend heavily on imports of natural gas and other commodities.Exports rose 3.8 per cent in the first quarter, the first such increase in a year, while consumer spending, which accounts for a hefty 60 per cent of total business activity in Japan, climbed 0.9 per cent as households bought more cars and other durable goods.The central bank, which is committed to 2 per cent inflation within two years, says it expects a moderate recovery by midyear but has warned that uncertainties in the domestic and global economies could foil those hopes.Abe needs fast results as ammunition in an election for the upper house of parliament in July, a vote that will determine his Liberal Democratic Party’s chances for pushing through with other policy priorities, such as revision of Japan’s war-renouncing constitution.Critics of the Abenomics strategy question whether the extra funding pumped into the economy will foster sustainable growth or just push up prices for shares and other assets.Key to the success of the policies will be increased spending by households and corporations, partly due to expectations that prices will rise. So far, increases in spending have been attributed mainly to luxury purchases by share investors splashing out after seeing gains in their portfolios.The first quarter data showed no pickup in corporate investment or in prices.Analysts had generally forecast a 2.7 per cent to 2.8 per cent increase in GDP in January-March and quarterly growth of about 0.7 per cent.Much of the growth in the first quarter of the year came from public demand: government spending on reconstruction from Japan’s March 2011 tsunami disaster and other public works. Private demand has been fueled by a recovery in housing investment, which has picked up sharply as purchasers rush to beat the expected increases in sales taxes.The sales tax increase, while needed to help reduce Japan’s massive public debt, will amount to a “major fiscal tightening,” said Jessop.To keep growth on track, the government will have to carry out fiscal and structural reforms — such as changes in labour, education and tax policies and administrative deregulation — to help improve Japan’s long-term competitiveness and adapt to its aging and shrinking population.In the near term, if companies do not boost wages to help improve household purchasing power, inflationary policies could just discourage consumer spending.Data released Wednesday showed consumer confidence fell slightly in April, though it has improved since late last year. by Elaine Kurtenbach, The Associated Press Posted May 16, 2013 5:44 am MDT Japan sees results from ‘Abenomics’ growth strategy, as GDP jumps 3.5 pct, beating forecasts
Column We need more creative enjoyable ways of managing chronic illnessColumn We need more creative enjoyable ways of managing chronic illness
Mags Mullarney is founder of Move4Parkinson’s. Further information on their ‘five elements’ self-management programme can be found on www.move4parkinsons.com. On Sunday29th of September a group from Move4Parkinson’s will travel to the World Parkinson’s Congress in Montreal, their progress at the conference can be followed via their blog on their website.Facebook: facebook.com/move4parkinsons IN LESS THAN four months I will mark a milestone event, it will be ten years since my diagnosis with Parkinson’s at the age of 47. Since then, there have been good days and there have been bad days, without a doubt though it has taken me on a journey I could never have expected, from completing my first ever marathon, to setting up a charity and establishing a choir for people with Parkinson’s their family members and friends – one which has released its first single and at the end of this week will travel to Montreal to both perform at and attend the World Parkinson’s Congress.It might seem that, like buses, you wait ten years for a story on Parkinson’s to come, and then three come at once. First was the news that Linda Ronstadt had stopped singing following a diagnosis of Parkinson’s, then the news that Billy Connolly has been diagnosed with early stage Parkinson’s, and just last week my good friend Shay Healy shared his personal Parkinson’s story, in his own searingly honest, at time humorous, at times challenging way, on TV3’s Midweek.Each of them is on their own unique journey with this often misunderstood illness, the second most common neurological condition after Alzheimer’s.My story though isn’t just about Parkinson’s, it is about our relationship with medicine and doctors in Ireland, it is about a new paradigm of healthcare that is needed for all chronic illness, one which is patient-led and holistic.We can’t continue doing things the old wayWe all know that our healthcare system is under-resourced and over stretched, we have one of the lowest ratios of neurologists to patients in all of Europe, but I don’t believe that the answer is to put more money into doing things in the same way that we always have.The truth is that we have a relationship with our healthcare professionals that doesn’t work. As patients we need to take more responsibility and ownership for our illnesses. Rather than just take our tablets and wait for our next appointment, it is vital that we understand what we are taking, why we are taking it, how it should work.We also need to look beyond medication; at exercise, nutrition, our mental well-being and other treatments which can form an effective arsenal in our battle against whatever illness it is that we happen to have.We are the ones who understand our illness better than any doctor might, we understand best how we, as unique individuals, are experiencing the illness we have. This is because we are living with our illnesses every day. If we pay attention, we will begin to really understand; how medicines make us feel when we take them in different ways, or at different times; which exercises support our well-being; or how our mental health is being affected by managing a chronic illness every day.Self management is not about ignoring expert adviceThis patient-led approach to healthcare is commonly known as ‘self-management’. It’s not about patients deciding alone what medications or other treatments will work for them, it’s about putting patients at the heart of their treatment. It’s about better communication between patients and healthcare providers and a multi-disciplinary approach that sees our professionals communicating with each-other; neurologists, GPs, physiotherapists, speech therapist and others, all working together with the patient to determine the best course of action.It might sound like a sensible approach, but we shouldn’t underestimate how far we currently are from that model and how much work it will take to change the culture and ways of working needed to get there.A first step, is for us as patients to educate ourselves. According to the WHO, among patients with chronic illness, approximately 50 per cent of us do not take medications as prescribed. This poor adherence to medication leads to increased morbidity and death and is estimated to incur costs of approximately $100 billion per year. It is vital that we take responsibility for learning how to manage our illnesses and take our medication.The comfort of a communityThis is where organisations such as Move4Parkinson’s come in. When I was diagnosed I had nowhere to turn, I was told not to research online because it would scare me, but even without doing it I was terrified, so I figured I had nothing to lose. What I found online was an amazing community of other people with Parkinson’s and specialists around the world.They were also realising that traditional approaches didn’t work, that regular exercise was hugely important for Parkinson’s, that changes as simple as taking medication with a glass of water would make it work better than just dry swallowing tablets.With Move4Parkinson’s we are working to make that information accessible in one place, in a simple way, that is easy to understand. We are working to educate people with Parkinson’s on how to manage their illnesses and how to work with their neurologists and health care workers to achieve the best possible quality of life. The 12,000 people with Parkinson’s living in Ireland deserve that at least.Uploaded by Move4ParkinsonsFeel in control againAs patients, regardless of what illness we have, we have to take ownership for our illnesses, empower ourselves, feel in control of our lives once again. As patient organisations, we can support those with chronic illnesses by teaching them self-management skills. A 2007 study showed that patients with high levels of engagement and active participation in their own care are ten times more likely to report high patient-satisfaction scores, five times more likely to report high quality-of-life scores and report significantly higher physical and mental functional status scores.We need to make self-management more accessible and to come up with more creative and (dare I say it) enjoyable ways, of managing chronic illness. This was one of the drivers for setting up our Move4Parkinson’s choir. It provides not just a sense of community but also supports the speech therapy needs of those with Parkinson’s, to improve and strengthen their vocal power.I believe that it is possible for the Irish healthcare system to move towards this model. This approach works, it has been proven in countries such as The Netherlands, with their ParkinsonsNet initiative, but we need everyone in our health care systems, including us patients, to get behind it in order for it to become a reality.
A guide wipes off snows outside the space museum located in Saint Paraskeva church in Pereyaslav-Khemlnytsky, a small town some 80 kilometers southeast of Kiev on 11 January 2019. Photo: AFPInside a traditional Orthodox church topped with a gold cross, instead of icons, visitors can see a lunar rover and the helmet of the first man in space Yuri Gagarin.The wooden church in central Ukraine is one of thousands of buildings that were repurposed or simply destroyed during an anti-religion campaign in the Soviet era.But now some believers are asking whether it’s time for the blue and grey painted structure to be returned to the Church, especially as Ukraine is undergoing a religious revival.Last month the country created its own Orthodox Church in a historic break with the Russian Orthodox Church, against a backdrop of its ongoing war with Russia-backed rebels in eastern Ukraine that has killed more than 10,000 people.”Today, when it is no longer forbidden to pray and believe in God, the church must be used as a place of worship,” said priest Mykhaylo Yurchenko, from the new Ukrainian Orthodox Church who serves in one of the nearby churches.Museum staff say clerics have visited and even tried out the acoustics, but there are no plans to reconsecrate it.”The museum was founded in the 1970s,” said Sergiy Volkodav, its 37-year-old chief curator.”It happened when space flights were wildly popular and every boy dreamed of becoming a cosmonaut,” he said, standing beside a spacesuit worn by cosmonaut Vyacheslav Zudov for a spacewalk in 1976.A guide waits for visitors at the space museum located in Saint Paraskeva church in Pereyaslav-Khemlnytsky, a small town some 80 kilometers southeast of Kiev on 11 January 2019. Photo: AFPBuilt in 1891, the Church of Saint Paraskeva houses over 450 exhibits, including a scarlet training parachute belonging to Gagarin, a collection of portraits of him and other personal items of the cosmonaut whose historic 1961 space flight made him a Soviet icon.The museum is part of a vast outdoor ethnographic complex, located in Pereyaslav-Khmelnytsky, a small town some 80 kilometres (50 miles) southeast of Kiev.’As cold as in space’ Soviet anti-religious propaganda used images of space exploration to persuade people that God did not exist.The Soviets also put some former churches to ideological use such as opening a museum of atheism in a cathedral in Leningrad, now Saint Petersburg.Some other churches were converted into planetariums.Volkodav said that, in opening a space museum in a church, the Soviet authorities’ intention was not necessarily to mock religion.They simply chose a building that could display large exhibits that include a model rocket several metres (feet) high, he said.Some, like Volkodav as well as priests and other locals, argue that the creation of the museum in fact saved the church from destruction.It formerly stood in a Cossack village that was deliberately flooded to build a vast reservoir in the 1960s.The church was one of the few buildings to be painstakingly dismantled and moved to a new location.One of those who lived in the village, Borys Stolyarenko, a 60-year-old mechanic, recalls services being held there in the early 1960s.”Later, when the Soviets turned it into a granary, we climbed through its windows with my friends and jumped down into the grain,” he said.He has no photographs of his former home village, he went on.”All I have is this church. The creation of the museum saved it,” he added.A guide waits for visitors at the space museum located in Saint Paraskeva church in Pereyaslav-Khemlnytsky, a small town some 80 kilometers southeast of Kiev on 11 January 2019. Photo: AFPToday though, the museum looks like it has seen better days. The exhibits are shabby and blue paint is flaking off the interior walls.Most visitors come in summer due to the lack of heating: a thermometer inside displays minus 10 degrees C (14 degrees F).”It’s as cold as in space,” joked a museum employee, wearing a sheepskin coat and hat.Use for worshipThe fall of the USSR and the proclamation of Ukraine’s independence in 1991, followed by religious freedom in this predominantly Orthodox country have not changed the museum’s status.Father Feodosiy from the local Orthodox monastery, loyal to the Moscow Patriarchate, said he would like to see the museum return to the Russian Orthodox Church.But if it were to go to the new Ukrainian Church, he would rather see it continue to host space exhibits, he said.”In the situation we have now, it’s better to have a museum there than those schismatics” from the independent Church, he said.Some locals have suggested moving the space exhibition to another location and opening a museum of religious icons in its place.But Volkodav is resolutely opposed.”This is the only space museum in a church in the whole world… it’s unique,” he claimed.
Roku Plans to Launch Amazon ChannelsLike Video Subscription Marketplace EXCLUSIVERoku Plans to Launch Amazon ChannelsLike Video Subscription Marketplace EXCLUSIVE
Roku plans to launch a marketplace for video subscription services in the coming months, which will allow consumers to sign up for and watch subscription services without the need to download separate apps on Roku devices, Variety has learned from multiple sources familiar with the company’s plans. The marketplace is said to be similar to Amazon Channels, a popular à la carte offering available on Fire TV devices.A Roku spokesperson declined to comment.Roku has long offered access to subscription services like HBO Now and CBS All Access via its channel store. Consumers who want to access any of these services need to download a dedicated app, also called channel in Roku’s vernacular, onto their streaming device, and then sign up for the service either through their TV or through the service provider’s website. In the future, Roku plans to bring together a number of these paid services in the same channel, making it easier to subscribe to, and then access any premium content, without the need to download and launch different apps. The company has also been working on the next generation of its billing platform, dubbed Roku Pay, to make it easier for consumers to pay for these services.This approach closely mimics Amazon Channels, a subscription video marketplace launched by the e-commerce giant in late 2015. Offered exclusively to Prime members, Amazon Channels offers consumers the ability to easily sign up for over 235 video subscription services directly from their Fire TV device. Once a consumer signs up for any of these paid channels, its content is not presented in a separate app, but right next to Amazon’s Prime Video catalog.The simplicity of Channels has led to Amazon becoming a major force in the à la carte subscription business: The Diffusion Group estimated recently that Amazon is selling more than 50% of all online HBO subscriptions in the U.S., far surpassing resellers like Apple and Google. Operators of smaller services have also told Variety in the past that Channels has become a major part of their business.Roku isn’t the only one taking a cue from Amazon: Bloomberg reported last month that Apple is looking to resell video subscriptions via its TV app, which is available on Apple TV and mobile devices. However, Apple’s subscription marketplace reportedly won’t launch before 2019, whereas Roku is looking to debut its service soon.Roku’s business model has long been about growing its audience with affordable streaming devices as well as partnerships with TV manufacturers, and then monetizing that audience through ads and services. The company does have some revenue share agreements with paid streaming services in place, but its biggest revenue contributor has been advertising. Revenue from ads and services surpassed Roku’s hardware revenue for the first time in the company’s history in Q1 of this year.One of the ways the company has grown its ad revenue has been the Roku channel, a free, ad-supported service that aggregates catalog titles from major Hollywood studios and other online content providers. In April, Roku added news from ABC, Cheddar, and others to the Roku Channel, which has since become one of the 10 most popular channels on the company’s devices. At this point, it’s unclear whether paid subscription services would also be directly integrated into the Roku Channel, or launch within a separate channel. Popular on Variety ×Actors Reveal Their Favorite Disney PrincessesSeveral actors, like Daisy Ridley, Awkwafina, Jeff Goldblum and Gina Rodriguez, reveal their favorite Disney princesses. Rapunzel, Mulan, Ariel,Tiana, Sleeping Beauty and Jasmine all got some love from the Disney stars.More VideosVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9Next UpJennifer Lopez Shares How She Became a Mogul04:350.5x1x1.25×1.5x2xLive00:0002:1502:15
Biochemists create computer controlled feedback loop with yeastBiochemists create computer controlled feedback loop with yeast
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further (PhysOrg.com) — Scientists of many varied backgrounds have been hard at work in recent years trying to figure out a way to control the intricate processes that go on in cells so as to allow them to manipulate them to do their bidding. Much of that work has involved trying to code the genes at the outset. Now a joint team of American and Swiss researchers, working out of ETH Zurich, has taken a completely different approach. As they describe in their paper published in Nature Biotechnology, they have figured out a way to create a feedback loop between a computer and yeast cells (Saccharomyces cerevisiae), to control the production of proteins. Researchers could use plant’s light switch to control cells © 2011 PhysOrg.com Citation: Biochemists create computer controlled feedback loop with yeast (2011, November 8) retrieved 18 August 2019 from https://phys.org/news/2011-11-biochemists-feedback-loop-yeast.html Their discovery rests on the fact that yeast cells have a molecule in them called phytochrome that serves as a sort of switch, causing changes within the genetic structure that turns on a protein producing process, when a red light is shined on it. Interestingly, a darker red light causes the opposite effect; in its presence, the yeast cells go back to their original genetic structure and stop making the protein. Thus, using just two kinds of light the researchers can cause protein production to start or stop at their whim.What would be more interesting though is if the protein production process could be controlled through a feedback loop. To make this happen, the team introduced a so-called reporter molecule into the yeast cells that turn on (go fluorescent) when protein is being produced. Unfortunately, cell processes can’t be made to do their thing within certain constraints, such as say, turn on or off at specific time rates or intervals. To get around this problem, the team built a computer model to figure out how long light pulses should last in order for the yeast cells to produce the proteins when they wanted them too. They then set the whole process to working.What they constructed was a process that starts with a computer telling a red light when to shine, thus setting the yeast cells into action. The computer then monitors the reporter cells to note first when they come on, indicating proteins are being made. When just the right amount of time has elapsed, the computer then commands the red light to cease and the darker light to go on to cause the protein production to cease. The whole process can go on and on automatically because of the feedback loop, with a constant amount of proteins being produced all the while. And that’s the beauty of the whole thing, because if researchers can control yeast cells in such a manner, other applications quickly spring to mind, such as making drugs or creating biofuels. Though it may take time, this new process could very well revolutionize the way biological processes are manipulated. More information: In silico feedback for in vivo regulation of a gene expression circuit, Nature Biotechnology (2011) doi:10.1038/nbt.2018AbstractWe show that difficulties in regulating cellular behavior with synthetic biological circuits may be circumvented using in silico feedback control. By tracking a circuit’s output in Saccharomyces cerevisiae in real time, we precisely control its behavior using an in silico feedback algorithm to compute regulatory inputs implemented through a genetically encoded light-responsive module. Moving control functions outside the cell should enable more sophisticated manipulation of cellular processes whenever real-time measurements of cellular variables are possible. Sacharomyces cerevisiae cells in DIC microscopy. Credit: Wikipedia.
AgeRelated Macular Degeneration AMD Market Key Trends Analysis Acucela Alimera SciencesAgeRelated Macular Degeneration AMD Market Key Trends Analysis Acucela Alimera Sciences
Age-Related Macular Degeneration (AMD) Market Get comprehensive research providing detailed regional analysis and growth outlook of the Global Age-Related Macular Degeneration (AMD) Market in the latest research report added by Big Market Research.Global Age-Related Macular Degeneration (AMD) Market is visual symptoms associated with dry age-related macular degeneration (AMD) is important for raising awareness of the condition and educating patients. a surge in the prevalence of eyerelated disorders and a rise in the global geriatric population boost the agerelated macular degeneration market. However, increase in the use of offlabel drugs and availability of offlabel therapies impedes the growth of the market.Request for a sample copy of this report @ https://www.bigmarketresearch.com/request-sample/3237744?utm_source=SHASHI-HTNThe report is an exhaustive analysis of this market across the world. It offers an overview of the market including its definition, applications, key drivers, key market players, key segments, and manufacturing technology. In addition, the study presents statistical data on the status of the market and hence is a valuable source of guidance for companies and individuals interested in the industry. Additionally, detailed insights on the company profile, product specifications, capacity, production value, and market shares for key vendors are presented in the report.The total market is further segmented based on company, country, and application/type for competitive landscape analysis. On the contrary, information on industry chain structure, emerging applications, and technological developments in the market makes the report a must-read document.The report reveals detailed information about the global key players as well as some small players of the Age-Related Macular Degeneration (AMD) sector.The information for each competitor includes:Company ProfileMain Business InformationSWOT AnalysisSales, Revenue, Price and Gross MarginMarket ShareThese insights help determine the strength of competition and take the necessary steps to obtain a leading position in the Age-Related Macular Degeneration (AMD) industry.Additionally, the research provides a detailed analysis of the key segments of the market with the help of charts and tables. An overview of each market segment such as type, application, and region are also provided in the report. These insights help in understanding the global trends in the Age-Related Macular Degeneration (AMD) industry and form strategies to be implemented in the future.The market across various regions is analyzed in the report, including North America, Europe, Asia-Pacific, and LAMEA. The report manifests the growth trends and future opportunities in every region. Additionally, the research provides a list of leading market players active in the Age-Related Macular Degeneration (AMD) industry.Avail the Discount on this Report @ https://www.bigmarketresearch.com/request-for-discount/3237744?utm_source=SHASHI-HTNThe key players explored in the industry include: Acucela, Alimera Sciences, Bayer Ag., F. Hoffmann-La Roche Ltd, Glaxosmithkline Plc, Neurotech PharmaceuticalsThe study clearly reveals that the Age-Related Macular Degeneration (AMD) industry has attained remarkable growth since 2024. This research report is prepared based on an in-depth analysis of the market by experts. As a final point, stakeholders, investors, product managers, marketing executives, and other professionals seeking unbiased data on supply, demand, and future forecasts would find the report valuable.Table of Contents Chapter 1 Executive SummaryChapter 2 Abbreviation and AcronymsChapter 3 Preface3.1 Research Scope3.2 Research Methodology3.2.1 Primary Sources3.2.2 Secondary Sources3.2.3 AssumptionsChapter 4 Market Landscape4.1 Market Overview4.2 Classification/Types4.3 Application/End UsersChapter 5 Market Trend Analysis5.1 Introduction5.2 Drivers5.3 Restraints5.4 Opportunities5.5 ThreatsChapter 6 Industry Chain Analysis6.1 Upstream/Suppliers Analysis6.2 Age-Related Macular Degeneration (AMD) Analysis6.2.1 Technology Analysis6.2.2 Cost Analysis6.2.3 Market Channel Analysis6.3 Downstream Buyers/End UsersReport Summary @ https://www.bigmarketresearch.com/report/3237744/global-age-related-macular-degeneration-amd-market-report-2019?utm_source=SHASHIAbout Us:Big Market Research has a range of research reports from various publishers across the world. Our database of reports of various market categories and sub-categories would help to find the exact report you may be looking for.We are instrumental in providing quantitative and qualitative insights on your area of interest by bringing reports from various publishers at one place to save your time and money. A lot of organizations across the world are gaining profits and great benefits from information gained through reports sourced by us.Contact us: Mr. Abhishek Paliwal5933 NE Win Sivers Drive, #205, Portland,OR 97220 United StatesDirect: +1-971-202-1575Toll Free: +1-800-910-6452Email email@example.com
News | Pediatric Imaging | August 14, 2019 Ultrasound Guidance Improves First-attempt Success in IV Access in Children August 14, 2019 – Children’s veins read more Related Content June 11, 2014 — Many people develop depression in the latest stages of life, but until now doctors had no idea that it could point to a build up of a naturally occurring protein in the brain called beta-amyloid, a hallmark of Alzheimer’s disease. In fact, late-life depression could become a major risk factor for developing Alzheimer’s faster than others, according to research unveiled at the Society of Nuclear Medicine and Molecular Imaging’s 2014 Annual Meeting (SNMMI).Alzheimer’s disease is a currently incurable neurodegenerative disease with marked protein aggregates including beta-amyloid and tau. The disease begins developing years before noticeable cognitive decline and memory loss. Depression has been proven to have its own neurodegenerative effects on the brain, but here researchers have found an undeniable connection between beta-amyloid in depressed elderly patients with cognitive deficits and advancement to Alzheimer’s disease. They were able to prove this using molecular imaging data from a global dementia imaging database.“Our results clearly indicate that mild cognitively impaired subjects with depressive symptoms suffer from elevated amyloid-levels when compared with non-depressed individuals,” said the study’s principal scientist Axel Rominger, M.D., from the department of nuclear medicine at the University of Munich in Germany. “The combination of elevated amyloid-levels and coexisting depressive symptoms constitute a patient population with a high risk for faster progression to Alzheimer’s disease.”The clinical study involved 371 patients with mild cognitive impairment who underwent PET imaging with the radiotracer F-18 florbetapir and magnetic resonance imaging (MRI) chosen retrospectively from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database, which includes data from at least 55 research centers across the United States and Canada now readily available to more than 2,500 researchers worldwide. Results showed that mild cognitive impaired patients with depressive symptoms had higher amyloid deposition than non-depressed controls as indicated by the binding of the radiotracer to amyloid particularly in the frontal cortex and the anterior and posterior cingulate gyrus of the brain, both involved in mood disorders such as depression.“Therapeutic options for Alzheimer’s disease are still limited and therefore the identification and understanding of contributing risk factors that influence the disease are crucial in ongoing research as they offer the possibilities for future medical intervention,” said co-author and fellow researcher Matthias Brendel. Additionally, knowing the risk could help patients make necessary lifestyle changes and prepare their families.For more information: www.snmmi.org FacebookTwitterLinkedInPrint分享 Image courtesy of UTHealth McGovern Medical School News | Radiation Therapy | August 15, 2019 First Patient Enrolled in World’s Largest Brain Cancer Clinical Trial Henry Ford Cancer Institute is first-in-the-world to enroll a glioblastoma patient in the GBM AGILE Trial (Adaptive… read more Images of regions of interest (colored lines) in the white matter skeleton representation. Data from left and right anterior thalamic radiation (ATR) were averaged. Image courtesy of C. Bouziane et al. Technology | Neuro Imaging | August 07, 2019 Synaptive Medical Launches Modus Plan With Automated Tractography Segmentation Synaptive Medical announced the U.S. launch and availability of Modus Plan featuring BrightMatter AutoSeg. This release… read more News | PET-CT | August 15, 2019 United Imaging Announces First U.S. Clinical Installation of uExplorer Total-body PET/CT United Imaging announced that its uExplorer total-body positron emission tomography/computed tomography (PET/CT) system… read more News | Stroke | August 16, 2019 Mobile Stroke Unit Gets Patients Quicker Treatment Than Traditional Ambulance Every second counts for stroke patients, as studies show they can lose up to 27 million brain cells per minute…. read more News | Neuro Imaging | August 16, 2019 ADHD Medication May Affect Brain Development in Children A drug used to treat attention-deficit/hyperactivity disorder (ADHD) appears to affect development of the brain’s… read more News | Brachytherapy Systems | August 14, 2019 Efficacy of Isoray’s Cesium Blu Showcased in Recent Studies August 14, 2019 — Isoray announced a trio of studies recently reported at scientific meetings and published in medica read more Feature | June 11, 2014 Depression in the Elderly Linked to Alzheimer’s Risk Molecular imaging study suggests late-life depression and beta-amyloid plaque in the brain could tip-off hastened development of the deadly dementia Image courtesy of Imago Systems News | Mammography | August 14, 2019 Imago Systems Announces Collaboration With Mayo Clinic for Breast Imaging Image visualization company Imago Systems announced it has signed a know-how license with Mayo Clinic. The multi-year… read more News | Artificial Intelligence | August 13, 2019 Artificial Intelligence Could Yield More Accurate Breast Cancer Diagnoses University of California Los Angeles (UCLA) researchers have developed an artificial intelligence (AI) system that… read more News | Cardiovascular Ultrasound | August 07, 2019 Contrast Use in First Transthoracic Echocardiogram for Heart Failure Reduces Repeat Testing Heart failure is the fourth most common cause for all admission to U.S. hospitals, and it is the most common reason for… read more
Transat highlights South and Cruise packages this summer seasonTransat highlights South and Cruise packages this summer season
Posted by Transat highlights South and Cruise packages this summer season Travelweek Group MONTREAL — Fresh off its strong showing at the Skytrax World Airline Awards earlier this month, Transat is reminding travellers that now is the time to book hassle-free summer vacations. The company offers a wide range of all-inclusive Sun packages and all-in-one cruise packages perfect for families, couples, groups and solo travellers.According to Geneviève LeBrun, Vice-President of Marketing at Transat Tours Canada, Transat’s Sun program comprises all-inclusive packages to 17 South destinations from Montreal, 12 from Toronto, four from Calgary and three from Vancouver and Edmonton. These packages come with a vast selection of resorts grouped under five collections: Luxury, Distinction, Family, Solo and Sun Savvy.And if clients prefer adventures at sea, LeBrun suggests one of Transat’s cruise packages. “Our cruise packages are perfect for those looking for a different experience and who want to discover several destinations in one trip. In short, with us, all travellers will find the vacation that caters to their desires,” she said.More news: Can you guess the top Instagrammed wedding locations in the world?Cruise packages include roundtrip flight with Air Transat, all transfers, the cruise and all taxes. There are about 10 itineraries in the Western, Eastern and Southern Caribbean from Fort Lauderdale, Miami and Havana.In addition, with Air Transat’s Flight Protection, travellers are sure to reach their destination in the event of a flight delay. They can also extend their trip, at no extra cost, by moving up their departure date up to 14 days before their cruise or by postponing their return to Canada up to 14 days after their journey at sea.Florida is also top of mind this summer, with Air Transat’s year-round direct flights to Orlando and Fort Lauderdale from Montreal and Toronto. Budget-friendly accommodations are available with Florida Holiday Homes in Kissimmee and south Orlando, featuring two to six bedrooms, fully-equipped kitchen, washer & dryer and a private pool. These homes are part of packages that include roundtrip flight with Air Transat, a seven-night stay and car rental.More news: Visit Orlando unveils new travel trade tools & agent perksFamilies who prefer to stay at a hotel will have plenty of choices, as Transat has recently added about 30 new properties to its roster in Fort Lauderdale, Miami, St. Petersburg, Orlando, Kissimmee and Tampa. Thursday, June 22, 2017 Tags: Transat << Previous PostNext Post >>
Top Stories Sponsored Stories Think Tank analyzes the second round of Democratic debates New high school in Mesa lets students pick career paths 5 things to look for when selecting an ophthalmologist “Now we can communicate with all our family,” said Maarouf’s aunt, Taghreed Eissa, who also has spent her life as a refugee in this Mediterranean city. “That makes it impossible for the new generation to forget the Palestinian cause.”“What happened to the Palestinians is what happened to the Jews before: They were dispersed throughout the world,” said Ali Khatib, 67, a Shaab man with relatives in Syria, Denmark, Canada and Saudi Arabia.Khatib’s family, too, was split by Israel’s creation: his father became an Israeli citizen while his uncle became a refugee in Lebanon. They lost touch. Then recently his son asked him about a man in Lebanon named Hisham Khatib whom he had just met online.His father pointed to a photo of his aunt and uncle on the living room wall.“Those are his grandparents,” he said.Also in Shaab, Houriya Faour, in her 70s, said that before social media, finding relatives was a struggle.“Now my son comes and tells me, this person says hello,” she said.Typing on a laptop, her son Mohammed, 36, opened a Facebook chat with a woman named Huda Faour whom he found while searching for his last name. “how r u can I ask u a question,” he wrote. “what are your mom’s and dad’s names?”Minutes later, he had found a new relative _ in Texas.Sitting in his travel agency in Shaab, Anwar Faour, 40, scrolled through his Facebook friends, pointing out relatives he has found in the United Arab Emirates, Syria, Lebanon, Dallas, Texas, and Los Angeles. He recalled his surprise as condolences poured in from all over the world upon the recent death of his uncle, a revered village council head.Across the border, Mona Maarouf followed the news of the uncle’s decline on Facebook and was the first to tell her side of the family when he died. Her grandfather and his father were brothers, among 11 siblings who ended up divided among Israel, Syria and Lebanon.The interest goes both ways.When Maarouf got engaged to a Palestinian man living in Sweden, Anwar Faour and his brothers in Israel saw photos of the couple online.“They asked for his number and called him and said, You take care of Mona,” Maarouf said.The engagement broke off, but Maarouf said the experience made her feel closer to her relatives.While Facebook strengthens ties, it also highlights differences. Associated PressSIDON, Lebanon (AP) – As Jewish forces advanced on their village during the war that surrounded Israel’s creation in 1948, the Palestinian Faour family piled children and belongings into donkey carts and fled, hoping to return home when the fighting stopped.Only some of them got back, and the family is still divided. Some are in the Lebanese city of Sidon as stateless refugees. Others are 80 kilometers (50 miles) away as Israeli citizens in their village of Shaab, across a fenced and hostile border. Meghan McCain to release audiobook on conservatism, family Faour, the travel agent, is an Israeli citizen and cannot enter most Arab countries. He speaks Hebrew and Arabic. Like many Arab citizens of Israel, he complains of discrimination by the state, but says he prefers it to living in a refugee camp.A cousin he corresponds with regularly, Larissa Ajjawi, has spent her life as one of Lebanon’s 436,000 Palestinian refugees who cannot become citizens, hold most jobs or buy property. She speaks Arabic but prefers to write in English or French.“We talk about general stuff: How are you, what’s going on, who got married, stuff like that,” said Ajjawi, 40, who lives in Beirut. “We never talk politics. I’d like to ask them what they think about things, but I can’t.”When asked separately, their views on the Israeli-Palestinian conflict differ substantially.For Ajjawi, who says she gets uncomfortable around Israelis when she travels abroad, the solution is simple: All the refugees should come back, and “All the Jews who have come to Palestine since 1948 should go back. They have their own countries.”For Faour, who never has lived outside Israel and has Jewish friends and colleagues, the solution is different, and not at all simple. Comments Share Arizona families, Arizona farms: providing the local community with responsibly produced dairy “All we want is for there to be peace and two states so that all people can live their lives,” he said.“Of course I want my relatives to come back and live here, but that’s not what Israel wants,” he said. “It’s a very hard question.”(Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.) More Valley freeways to be closed this weekend for improvements Granddaughter Mona Maarouf, 26, still considers Shaab home, even though she has spent her life in Sidon, has never visited her ancestral village and maybe never will. She knew she had relatives there but knew nothing about them.Then she joined Facebook.Now she tracks who has died in the village, and her cousins in Israel weigh in on her marriage prospects. “I didn’t think anyone knew anything about me,” she says. “Then I saw that they knew everything.”Social media have produced a boom in communications between Palestinians in Israel and the Arab world, once connected only through rare letters carried by intermediaries or the International Red Cross. Younger exiles like Maarouf are tracking down and getting to know relatives separated for decades.Many Palestinians say they now know more about their extended families than at any time since the birth of Israel, an event Palestinians mourn every May 15 as the “Nakba,” or catastrophe.Mostly they stick to swapping family photos and news, worrying that political talk could draw attention from intelligence agencies. Some, however, say stronger ties will bolster the Palestinian demand that some 5 million Palestinian refugees registered with the U.N. return to their villages, a demand that Israel rejects, saying it would destroy the Jewish state. Clean energy: Why it matters for Arizona
United and Continental to merge and create new airlineUnited and Continental to merge and create new airline
“Building on our Star Alliance partnership, we are creating a stronger, more efficient airline, both operationally and financially, better positioned to succeed in a dynamic and highly competitive global aviation industry,” adds Mr Tilton.In a joint statement, the two carriers pledged to serve all the communities each carrier currently operates to under the merged entity. The new United will carry more than 144 million passengers per year and fly to 370 destinations in 59 countries.With the merger expected to be complete in the fourth quarter of this year, the CEO will keep headquarters in both Chicago and Huston. But the new airline’s operational headquarters will be located in Chicago, the current headquarters of United Airlines.Houston, which is currently the headquarters of Continental, will continue to see a strong presence from the merged company and will be the new airline’s largest hub.Unions say support will only come with job protectionFlight attendant unions have already spoken out on the new merger, saying their support will only be given if the two carriers agree on a contract with pay, benefit and work rule improvements.“They cannot move forward without various approvals by the government, other constituencies and agreements with labor,” said Greg Davidowitch, Association of Flight Attendants-CWA President at United. “Integration of inflight operations could take years to complete and it will not occur at all unless we can support the deal with the protection of our jobs and improvement of our careers upfront.” United Continental Dreamliner in new livery. Heads of United and Continental, Glenn Tilton and Jeff Smisek. United Airlines and Continental Airlines have formally announced that they will be merging and creating a brand new integrated entity, which will keep the United name but fly the Continental livery and logo.If approved by regulators and shareholders the two companies will merge under a new umbrella company called United Continental Holdings. The airline created from the all-stock merger will be flying to 370 destinations around the world.Jeff Smisek, Continental Chairman, President and CEO, will lead the new company as its CEO and also sit on the board as Chairman. Glenn Tilton, United Chairman, President and CEO will step back and serve as a non-executive Chairman.“Together, we will have the financial strength necessary to make critical investments to continue to improve our products and services and to achieve and sustain profitability,” said Mr Smisek.“We have forged a highly collaborative partnership with United over the past two years as we prepared for and executed a seamless transition to Star Alliance, an important achievement that gave us valuable experience in working together and built mutual respect between our two companies.”In late 2009 when Continental made the transition from SkyTeam into Star Alliance it had indicated the move was so that it could further cooperate with United Airlines. Source = e-Travel Blackboard: W.X
Si Travel Group acquires Freestyle HolidaysSi Travel Group, last week entered into an agreement to acquire Freestyle Holidays from Pinpoint Travel Group, which also includes the license to operate Rosie Holidays in Australia.Freestyle Holidays is Australia’s largest independent wholesaler of travel solutions providing product from all major destinations worldwide including USA, Hawaii, Maldives, Thailand, Vietnam, Bali, Malaysia, Singapore, Hong Kong, China, Australia and Vanuatu.The acquisition, effective December 1, will be Si Travel Group’s first major acquisition as it looks to position itself as a leader in wholesale distribution and service products in the travel industry.Tui Eruera, Managing Director of Si Travel Group, said “We are very excited to be taking on such a well-respected Australian wholesale business as it will significantly scale and broaden our expertise in the travel industry and form a solid base for further business developments in the future.”This acquisition forms a key part of Si Travel Group’s business acquisition strategy to seek growth opportunities in the travel and tourism sector.“We have an appetite for businesses that can be improved through technology, and we see Freestyle Holidays as an opportunity to invest and incorporate new technology platforms to accelerate growth.”Freestyle Holidays will be moved from their current Rozelle offices to Si Travel Group’s headquarters in Balmain. Source = Si Travel Group
The 10 millionth passenger to use a Cyprus airport this year left Larnaca airport on Monday morning with a special celebration to mark the milestone.According to Hermes Airport, the number of passengers travelling through Paphos and Larnaca airports in 2017 reached 10 million.The milestone passenger was Latvian citizen German Gedmintas a permanent resident in Cyprus who was leaving Larnaca on a flight to Brussels.Within the first six months of the year, Larnaca airport had the third greatest passenger increase across Europe in the category for passenger traffic spanning from five to 10 million per year, data from ACI (airports council international) Europe, reveals.The 22 per cent increase corresponded to 571,926 more passengers.Transport Minister Marios Demetriades said there was no room for complacency.“It is a very important day,” he said. “For Cypriot air transport it is after all a remarkable number, 10 million passengers.”Demetriades added that passenger traffic had recorded a 45 per cent rise in recent years. When the current administration took over in 2013, the number was seven million.The minister congratulated airport operator Hermes for the good work and the infrastructure it provides passengers.“As a government we support all these efforts, either through the open skies policy we have adopted in recent years or the incentives we provide with Hermes, or as the Cyprus tourism organisation.”Chairman of Hermes Panayiotis Hadjipantelis said it took a lot of work to increase and maintain passenger numbers.“The immediate tackling of the structural problems and dysfunctions in the tourism sector must be an irrevocable goal, as was the repositioning of our tourist identity,” he said. “The challenge is there, considering that the prospects exist.”Based on Hermes’ forecasts, the year will close with around 10.2 million passengers moving through both airports, up by 14 per cent on 2016.You May LikeYahoo SearchThese SUVs Are The Cream Of The Crop. Research Best Compact SUV CarYahoo SearchUndoKelley Blue Book10 Electric Cars That Last the LongestKelley Blue BookUndoDr. Marty ProPower Plus Supplement3 Dangerous Foods People Feed Their Dogs (Without Realizing It)Dr. Marty ProPower Plus SupplementUndo Concern over falling tourism numbersUndoTurkish Cypriot actions in Varosha ‘a clear violation’ of UN resolutions, Nicosia saysUndoOur View: Argaka mukhtar should not act as if he owns the beachUndoby Taboolaby Taboola
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